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Histological Evaluation of Ankaferd Blood Stopper, Ferric Sulfate and Formocresol As Pulpotomy Agents in Rat Molars
1Department of Pediatric Dentistry, Faculty of Dentistry
2Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayis University
Journal of Pediatric Dentistry 2013; 1(2): 32-36 DOI: 10.4103/WKMP-0028.117441
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The aim of this study is to evaluate the use of Ankaferd blood stopper (ABS) as a pulpotomy agent in rat molars and to compare it to ferric sulfate (FS) and formocresol (FC). Pulpotomies of 72 rat molar teeth were performed with ABS, FS and FC. Access cavities were sealed with Intermediate Restorative Material. Histological evaluations were conducted at 7, 15 and 30 days post-operatively. Statistical analysis was performed using the Kruskal-Wallis and Dunn′s multiple comparison tests. There was no significant difference in inflammatory cell response between groups at 7 and 15 days (P > 0.05). However, at 30 days, a higher density of inflammatory cells was observed in the FC group when compared with the other groups (P < 0.05). No significant differences in hard-tissue formation were observed between groups at any time tested. Based on the histological findings of this study, ABS may be considered an acceptable alternative to FC and FS for primary teeth pulpotomies. Further, clinical research is needed to confirm this finding.